Bioavailability of Drugs to the Brain and the Blood-Brain Barrier

摘要

The main reason for planning the technical review was to determine the importanceof BBB (Blood-Brain Barrier) research findings to drug abuse research. In planning the review, it was confirmed that drug abuse researchers must be constantly aware of findings about the BBB. The chapters herein demonstrate the importance of the BBB in understanding drug abuse and affirm that the various roles of the BBB have to be understood to fully comprehend the mechanisms of CNS effects of drugs, including drugs of abuse, and the treatment of drug abuse. The central effects of drugs are not isolated from their effects on the BBB nor from the effects of the BBB on the drugs.