Method of Analysis and Quality Assurance Practices by the U.S. Geological Survey Organic Geochemistry Research Group-Determination of Geosmin and Methylisoborneol in Water using Solid-Phase Microextraction and Gas Chromatography/Mass Spectrometry

摘要

An analytical method for the determination of glyphosate, its principal degradation compound, aminomethylphosphonic acid (AMPA), and glufosinate in water with varying matrices has been developed. Four different sample matrices forti.ed at 0.2 and 2.0 micro g/L (micrograms per liter) were analyzed using precolumn derivatization with 9-fluorenylmethylchloroformate (FMOC). After derivatization, cleanup and concentration were accomplished using automated online solid-phase extraction followed by elution with the mobile phase allowing for direct injection into a liquid chromatograph/mass spectrometer (LC/MS). Analytical conditions for MS detection were optimized, and quantitation was carried out using the following representative ions: 390 and 168 for glyphosate; 332, 110, and 136 for AMPA; and 402, 180, and 206 for glufosinate.