Report of the Special Emphasis Panel on Opportunities and Obstacles to Genetic Research in NHLBI Clinical Studies

摘要

In order for NHLBI-supported studies to respond effectively, quickly, and in a coordinated fashion to opportunities for genetic research, a significant number of serious potential impediments and issues must be addressed, ranging from informed consent to prioritizing and expediting requests for access to stored samples. As a consequence, the National Heart, Lung and Blood Institute (NHLBI) convened a Special Emphasis Panel (SEP) on the Opportunities and Obstacles to Genetic Research in NHLBI Clinical Studies to chart a course for future research efforts. The SEP was charged to: Address the critical issues, barriers, and needs to permit optimal use of collected clinical samples. Address issues relating to collecting and sharing samples in future NHLBI studies. Recommend a comprehensive master plan of activities to facilitate genetic in NHLBI clinical research. This document is intended to guide the decision-making process of the National Heart, Lung, and Blood Advisory Council.