Methadone Diversion, Abuse, and Misuse: Deaths Increasing at Alarming Rate

摘要

From 1999 through 2006 the number of methadone-related deaths increased significantly. Most deaths are attributed to the abuse of methadone diverted from hospitals, pharmacies, practitioners, and pain management physicians. Some deaths result from misuse of legitimately prescribed methadone or methadone obtained from narcotic treatment programs, including use in combination with other drugs and/or alcohol. Methadone is a safe and effective drug when used as prescribed; however, when it is misused or abused, particularly in combination with other prescription drugs, illicit drugs, or alcohol, death or nonfatal overdose is likely to occur. This assessment analyzes increases in methadone diversion, abuse, and misuse that have occurred since 1999.