Modeling Heterogeneity in Susceptibility and Infectivity for HIV Infection

摘要

The paper discusses the dynamics of heterogeneity in HIV spread and develops atheory of heterogeneity in susceptibility and infectivity within a population that allows a simple representation of key phenomena within an epidemic model. It is suggested that the effects of heterogeneity-related phenomena can be captured by letting two key parameters, the mean susceptibility over time of the uninfected and the mean infectivity of the infected, depend upon the proportion of the population that is uninfected. (Copyright (c) 1989 by Springer-Verlag.)