Study of the Mechanism of Carcinogenesis by Carcinogens Which Are Negative in the Ames Test. Progress Report, April 1-September 1, 1979

摘要

Carcinogens ethionine, thioacetamide, and actinomycin D, all of which are negative in the Ames test and all of which raise the progesterone level in the chicken, were tested to determine their physiological role in carcinogenesis. The optimization of the carcinogenesis model also included evaluation of the chicken as the biological indicator of physiological changes relative to the above compounds. (ERA citation 05:003658)