Pressure Mediated Reduction of Ultrasonically-Induced Cell Lysis

摘要

Chinese hamster V-79 cells, exposed in polystyrene tubes for 5 min to 1 MHz continous wave ultrasound, were lysed more by a 10W/cm exp 2 than a 5W/cm exp 2 intensity. Higher atmospheric pressure was needed to eliminate lysis with the former relative to the latter intensity, but lysis by 10W/cm exp 2 was completely eliminated with 2 atmospheres of hydrostatic pressure. The reduction in lysis per unit increase in atomspheric pressure was comparable for both ultrasound intensities. (ERA citation 06:016227)