Radiation Dose Estimates and Hazard Evaluations for Inhaled Airborne Radionuclides. Annual Progress Report July 1981-June 1982.

摘要

The objective of this project is to conduct confirmatory research on aerosol characteristics and the resulting radiation dose distribution in animals following inhalation and to provide prediction of health consequences in humans due to airborne radioactivity which might be released in normal operations or under accident conditions during production of nuclear fuel composed of mixed oxides of U and Pu. Four research reports summarize the results of specific areas of research. The first paper details development of a method for determination of specific surface area of small samples of mixed oxide or pure PuO2 particles. The second paper details the extension of the biomathematical model previously used to describe retention, distribution and excretion of Pu from these mixed oxide aerosols to include a description of Am and U compononts of these aerosols. The third paper summarizes the biological responses observed in radiation dose pattern studies in which dogs, monkeys and rats received inhalation exposures to either 750 C heat treated UO2 + PuO2, 1750 C heat-treated (U, Pu)O2 or 850 C heat-treated 'pure' PuO2. The fourth paper described dose-response studies in which rats were exposed to (U, Pu)O2 or 'pure' PuO2. This paper updates earlier reports and summarizes the status of animals through approximately 650 days after inhalation.