Chemical Characterization and Toxicologic Evaluation of Airborne Mixtures. Tumorigenicity Studies of Diesel Fuel-2, Red Smoke Dye and Violet Smoke Dyes in the SENCAR Mouse Skin Tumorigenesis Bioassay System

摘要

The tumorigenicities of Diesel Fuel-2, Red Smoke Dye and Violet Smoke Dye were tested in the SENCAR Mouse Skin Bioassay System. The Diesel Fuel-2 gave a signigificant tumor response when tested as a tumor promoter but negative results when tested as a complete carcinogen. There were no tumor responses to either the Red or Violet Smoke Dyes when tested as a complete carcinogens. Although a few tumors occurred in the Red and Violet Smoke Dye tumor initiation studies, the response was not significantly different from that of the controls. 29 refs., 10 tabs. (ERA citation 10:050012)