MRI-Based Screen for Breast Cancer Patients Carrying a Breast Cancer Susceptibility Gene

摘要

To date, breast MRI screening studies have been performed in 165 women. These examination prompted breast biopsy in 15 women, 4 of which yielded malignancy. Results to date demonstrate the feasibility of using breast MRI to screen high risk women. In particular, adherence to strict architectural interpretation criteria has minimized false positive findings. Additional data is required before any statements of the potential efficacy of MRI can be made. This work has been critical to the development of a multi-center pilot trial of breast MRI screening in high risk populations.