Cellular and Molecular Responses to Depressed Metabolism and Low Temperatures

摘要

The overall goal of the APS Intersociety Meeting entitled 'The Power Of Comparative Physiology: Evolution Integration And Applied', held from August 24-28, 2002 in San Diego, California, was to bring together comparative biologists who utilize a diversity of approaches including molecular, cellular, organ, and organismal physiology/biochemistry, functional morphology, biomechanics and biophysics, ecology and evolutionary biology to understand physiological processes and traits. The aim of the symposium supported by the ONR was to present recent advances in gene expression and cellular signaling pathways that mediate adaptive responses to low body temperatures and metabolic depression. Several of the talks focused on the use of new approaches from genomics and proteomics to elucidate pathways that permit survival during altered thermal and metabolic states. The symposium contained presentations on organisms ranging from lower vertebrates to mammals in order to identify common mechanisms as well as alternative pathways of adaptation.