Endocrine and Metabolic Response of Dogs to Whole-Body Vibration

摘要

To determine the endocrine and metabolic response of restrained dogs to whole-body vibration, pentobarbital anesthetized and non-anesthetized dogs were vibrated along the z axis while restrained in dorsal recumbency. After vibration of anesthetized dogs at either 4 cps, 0.4 g for 30 minutes or 2 hours, or at 10 cps, 2.3 g for 2 hours, there was an average increase of 4.08 mcg 17 hydroxycorticosteroids (17-OH-CS) per 100 ml plasma and a significant increase in blood epinephrine but not serotonin or norepinephrine. Shaking at 4 cps, 1.7 g for 30 minutes produced less of a change in plasma 17-OHCS than at 0.4 g. However, shaking at 4 cps for 6 hours led to greater increase in plasma 17-OH-CS at 1.7 g than 0.4 g. Non-anesthetized dogs shaken at 4 cps for 30 minutes had a greater increase of plasma 17-OH-CS than similarly shaken anesthetized dogs. Possible mechanisms for alterations in endocrine function are discussed. (Author)