The Effect of Iron on the Virulence and Immonogenicity of Avirulent Pasteurella Pestis Strains

摘要

In passage of avirulent Past. pestis strains (vaccine strains EV and No. 1) through the organism of albino mice with a simultaneous administration of iron protosulfide there was a considerable rise in the residual virulence of the mentioned strains. Cultures of EV and No. 1 strains passaged through the organism of albino mice with a simultaneous administration of the iron salt become more immunogenic for guinea pigs as compared to the initial cultures of these strains. (Author)