Mebendazole Treatment for Intestinal Nematodes in a Philippine Barrio.

摘要

Mebendazole in doses of 200 mg. per day for 4 days was used in the mass treatment of Ascaris lumbricoides, Trichuris trichiura and hookworm among 585 inhabitants of Barrio Tallaoen, Tagudin Ilocos Sur; children below 6 years of age were given half the dose. This treatment was repeated every 2 months for 10 months. The treatment effected a dramatic change in the nematological profile of the barrio inhabitants: the pre-treatment prevalences of 78%, 88%, and 31% for A. lumbricoides, T. trichiura and hookworm, respectively, decreased significantly after the 3rd treatment to 5%, 8%, and 3%, and after the 6th treatment to 3%, 9% and 2%, respectively. Mebendazole was found to be well tolerated by all age groups.