Circulation and Hemostatic Effectiveness of Platelets Stored at 4 C or 22 C: Studies in Aspirin-Treated Normal Volunteers.

摘要

Obviously, data obtained from studies of platelet viability and function in normal volunteers treated with aspirin cannot be applied directly to patients with thrombocytopenia. However, these data support the recommendation that patients with dilutional thrombocytopenia secondary to massive blood transfusion or with thrombocytopenia secondary to platelet destruction during extracorporeal circulation should be treated with platelets that have been stored at 4 C, whereas prophylactic treatment of thrombocytopenia produced by impaired platelet production may be better treated with platelets that have been stored at 22 C.