Evoked Potentials to Evaluate Mechanisms of Peripheral Nerve Repair Including Computerized, Non-invasive Recording.

摘要

The purpose of these studies is to develop earlier and more accurate methods of evaluating peripheral nerve injuries than are commonly in use. Nerve action potential recording has been combined with evoked muscle action potential and muscle tension studies to study a number of experimental problems and has been compared with electromyography, nerve stimulation, and clinical examination to study a large series of human neuromas in continuity. Computerized methods for evaluating nerve injuries in a non-invasive fashion have also been developed. Recent experimental work has focused on comparison of interfasicular graft repair with fasicular repair and end-to-end repair in a large group of primates using light histologic electron microscope, and electrical methods to evaluate results. During the past year, an implantable system for stimulating muscle in a long-term repetitive fashion has been designed and placed in a few animals and design of a radio-frequency triggering system is currently being worked on. In addition, our large clinical experience with nerve injuries has undergone computer storage and early analysis of some features, particularly the electrophysiologic ones, has been completed. (Author)