Fungitoxicity of Ortho, Meta and Para-Hydroxybenzalanilines

摘要

2-Hydroxybenzalaniiines (la-Xla), 3-hydroxybenzalanilines (Ib-Xlb) and 4-hydroxybenzalanilines (Ic-XIc) were synthesized by condensing 2-hydroxybenzaldehyde, 3-hydroxybenzaldehyde and 4-hydroxybenzaldehyde with aniline and substituted anilines in equimolar ratio. The crude products were recrystallized from ethanol and characterized on the basis of elemental analysis and spectral studies. The synthesized hydroxyl substituted benzalanilines were screened in vitro for antifungal potential against Alternaria alternata, Fusarium oxysporum and Myrothecium roridum by spore germination inhibition method at various concentrations. The antifungal potential has been expressed in terms of ED_(50) values.