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A rigid motion correction method for helical computed tomography (CT)

机译:一种用于螺旋计算机断层扫描(CT)的刚性运动校正方法

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We propose a method to compensate for six degree-of-freedom rigid motion in helical CT of the head. The method is demonstrated in simulations and in helical scans performed on a 16-slice CT scanner. Scans of a Hoffman brain phantom were acquired while an optical motion tracking system recorded the motion of the bed and the phantom. Motion correction was performed by restoring projection consistency using data from the motion tracking system, and reconstructing with an iterative fully 3D algorithm. Motion correction accuracy was evaluated by comparing reconstructed images with a stationary reference scan. We also investigated the effects on accuracy of tracker sampling rate, measurement jitter, interpolation of tracker measurements, and the synchronization of motion data and CT projections. After optimization of these aspects, motion corrected images corresponded remarkably closely to images of the stationary phantom with correlation and similarity coefficients both above 0.9. We performed a simulation study using volunteer head motion and found similarly that our method is capable of compensating effectively for realistic human head movements. To the best of our knowledge, this is the first practical demonstration of generalized rigid motion correction in helical CT. Its clinical value, which we have yet to explore, may be significant. For example it could reduce the necessity for repeat scans and resource-intensive anesthetic and sedation procedures in patient groups prone to motion, such as young children. It is not only applicable to dedicated CT imaging, but also to hybrid PET/CT and SPECT/CT, where it could also ensure an accurate CT image for lesion localization and attenuation correction of the functional image data.
机译:我们提出了一种方法来补偿头部的螺旋CT的六个自由度的刚性运动。该方法在模拟和在16层CT扫描仪上进行的螺旋扫描中得到了证明。在光学运动跟踪系统记录床和体模的运动的同时,获取了霍夫曼脑部模型的扫描图像。通过使用运动跟踪系统中的数据恢复投影一致性并使用迭代的全3D算法进行重构,可以进行运动校正。通过将重建图像与固定参考扫描进行比较来评估运动校正的准确性。我们还研究了对跟踪器采样率,测量抖动,跟踪器测量的内插以及运动数据和CT投影同步的准确性的影响。在对这些方面进行优化之后,经过运动校正的图像与固定体模的图像非常接近,其相关系数和相似系数均在0.9以上。我们使用志愿者的头部运动进行了模拟研究,并且类似地发现,我们的方法能够有效地补偿现实的人类头部运动。据我们所知,这是螺旋CT中广义刚体运动校正的首次实际演示。我们尚未探索的临床价值可能很重要。例如,它可以减少对容易运动的患者群体(例如年幼的孩子)进行重复扫描以及资源密集型麻醉和镇静程序的必要性。它不仅适用于专用的CT成像,而且还适用于混合PET / CT和SPECT / CT,在此还可以确保准确的CT图像,用于病变定位和功能图像数据的衰减校正。

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