首页> 外文期刊>Physics in medicine and biology. >Measured count-rate performance of the Discovery STE PET/CT scanner in 2D, 3D and partial collimation acquisition modes.
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Measured count-rate performance of the Discovery STE PET/CT scanner in 2D, 3D and partial collimation acquisition modes.

机译:在2D,3D和部分准直采集模式下,Discovery STE PET / CT扫描仪的测量计数率性能。

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摘要

We measured count rates and scatter fraction on the Discovery STE PET/CT scanner in conventional 2D and 3D acquisition modes, and in a partial collimation mode between 2D and 3D. As part of the evaluation of using partial collimation, we estimated global count rates using a scanner model that combined computer simulations with an empirical live-time function. Our measurements followed the NEMA NU2 count rate and scatter-fraction protocol to obtain true, scattered and random coincidence events, from which noise equivalent count (NEC) rates were calculated. The effect of patient size was considered by using 27 cm and 35 cm diameter phantoms, in addition to the standard 20 cm diameter cylindrical count-rate phantom. Using the scanner model, we evaluated two partial collimation cases: removing half of the septa (2.5D) and removing two-thirds of the septa (2.7D). Based on predictions of the model, a 2.7D collimator was constructed. Count rates and scatter fractions were then measured in 2D, 2.7D and 3D. Thescanner model predicted relative NEC variation with activity, as confirmed by measurements. The measured 2.7D NEC was equal or greater than 3D NEC for all activity levels in the 27 cm and 35 cm phantoms. In the 20 cm phantom, 3D NEC was somewhat higher ( approximately 15%) than 2.7D NEC at 100 MBq. For all higher activity concentrations, 2.7D NEC was greater and peaked 26% above the 3D peak NEC. The peak NEC in 2.7D mode occurred at approximately 425 MBq, and was 26-50% greater than the peak 3D NEC, depending on object size. NEC in 2D was considerably lower, except at relatively high activity concentrations. Partial collimation shows promise for improved noise equivalent count rates in clinical imaging without altering other detector parameters.
机译:我们在传统的2D和3D采集模式下以及在2D和3D之间的部分准直模式下,在Discovery STE PET / CT扫描仪上测量了计数率和散射分数。作为使用部分准直的评估的一部分,我们使用结合了计算机模拟和经验实时功能的扫描仪模型来估算整体计数率。我们的测量遵循NEMA NU2计数率和散射分数协议,以获得真实,分散和随机的重合事件,从中计算出噪声当量计数(NEC)率。除了使用标准的20厘米直径的圆柱计数率幻像外,还考虑使用27厘米和35厘米直径的幻像来考虑患者体型的影响。使用扫描仪模型,我们评估了两个部分准直的情况:去除隔垫的一半(2.5D)和去除隔垫的三分之二(2.7D)。根据模型的预测,构造了一个2.7D准直仪。然后以2D,2.7D和3D测量计数率和散射分数。扫描仪模型预测了NEC随活性的相对变化,已通过测量证实。对于27 cm和35 cm幻像中的所有活动水平,所测得的2.7D NEC等于或大于3D NEC。在20厘米幻影中,在100 MBq处3D NEC比2.7D NEC稍高(大约15%)。对于所有较高的活性浓度,2.7D NEC更高,并且比3D峰值NEC峰值高26%。 2.7D模式下的峰值NEC发生在大约425 MBq,并且比3D NEC峰值大26-50%,具体取决于对象大小。除了在相对较高的活性浓度下,二维的NEC明显较低。部分准直显示了在不改变其他检测器参数的情况下改善临床成像中噪声等效计数率的希望。

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