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Battlefield medicine: disrupting (bio) pharmaceutical production

机译:战地医学:破坏(生物)制药生产

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摘要

Conventional pharmaceutical manufacturing, whose outdated processes are fraught with significant operational and logistical issues, fails to address the 'on demand' needs of today's military and civilian patient populations. Recent advances within the DARPA Battlefield Medicine program suggest that innovative and flexible platforms for producing Pharmaceuticals and biologies can be developed that minimize waste, improve capacity to handle wide-ranging operational conditions, and manufacture multiple types of therapeutics - all within short time frames. A distributed 'on demand' therapeutics manufacturing system obviates the need for individual drug stockpiling, cold storage requirements and complex logistics, while enabling cost-effective production of small quantities of medications, such as orphan drugs, and permits the flexibility and responsiveness required in manufacturing to adequately meet the general supply chain needs.
机译:传统的制药生产工艺过时,充满了重大的运营和后勤问题,无法满足当今军事和平民患者群体的“按需”需求。 DARPA战地医学计划的最新进展表明,可以开发出创新且灵活的生产药品和生物制剂的平台,以最大程度地减少浪费,提高处理各种操作条件的能力以及制造多种类型的疗法-所有这些都可以在短时间内完成。分布式“按需”疗法生产系统消除了对单个药物库存,冷藏需求和复杂物流的需求,同时能够经济高效地生产少量药物(例如孤儿药),并允许制造过程中所需的灵活性和响应能力以充分满足一般供应链的需求。

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