STRUCTURE OF CHEMICAL COMPOUNDS, METHODS OF ANALYSIS AND PROCESS CONTROL CURRENT STATE OF IR SPECTROSCOPY APPLIED TO PHARMACEUTICAL ANALYSIS

摘要

IR spectroscopy is at present one of the leading methods in many branches of science. It is widely used in the analysis and quality control of drugs [1 - 3]. It is well-known that IR-radiation is by nature electromagnetic and lies in the spectral region between the red end of visible light and shortwave radio waves. Glagoleva-Arkadeva showed already in 1923 that there is a continuous transition from visible radiation to infrared to radio waves, i.e., there are no distinct boundaries between these ranges of radiation. Namely this explains the fact that different boundaries of the IR region are used in the scientific and educational literature. It is situated approximately between 14,000 and 20 cm and is arbitrarily divided into the near or NIR (from 0.74-0.78 to 2 mum or from 13,300 to 5,000 cm), middle (from 2 to 25 mum or from 5,000 to 400 cm), and far (from 25 to 1,000 mum or from 400 to 10 cm) [4, 5].