Synthesis and characterisation of some Co(II), Cu(II) and Ni(II) complexes with nicotinoylhydrazine derivatives and the biological role of metals and anions (SO42-, NO3-, C2O42- and CH3CO2-) on the antibacterial properties

摘要

A series of biologically active complexes of cobalt(II) and nickel(II) with nicotinoylhydrazine derived compoundshaving the same metal ion but different anions, such as sulphate,nitrate, oxalate and acetate, have been synthesised andcharacterised on the basis of their physical, analytical and spectraldata. In order to understand the possible role of anions on theantibacterial properties, these synthesised compounds and theirmetal complexes with various anions have been screened againstthe bacterial species Escherichia coli, Pseudomonas aeruginosaand Staphylococcus aureus. These title studies have indicated adecisive role of anions in increasing the antibacterial properties.