Synthesis of novel thioamidoalkyl-, thiocarbamidoalkyl naphthols via a three-component condensation reaction using heterogeneous catalyst of ferric hydrogensulfate

摘要

Ferric hydrogensulfate [Fe(HSO _4) _3] was used as a suitable heterogeneous catalyst for the one-pot multicomponent reaction of b-naphthol, aromatic aldehydes, and thioamide derivatives to obtain the corresponding thioamidoalkyl naphthols. Various novel thioamidoalkyl naphthols and thiocarbamidoalkyl naphthols were synthesized in good yields from thioacetamide and thiourea. The heterogeneous nature of the catalyst made it reusable for further chemical reactions.