Spatial profiling of analyte signal intensities in inductively coupled plasma mass spectrometry

摘要

While much of the spatial profiling research in ICP-MS has been devoted to optimization of sampling position as a function of power and aerosol carrier gas flow rate,the evolution of knowledge of ICP-MS can be traced through the publications of these fundamental studies.Axial profiling,which provides information on the energy and time needed to form a given ion,is also useful when establishing the optimal operating conditions,and can be used to assess if a matrix induces earlier desolvation.However,radial profiling can provide valuable insight into the predominant ionization mechanism(s) in the TCP,which can,in turn,facilitate the selection of an efficient internal standard.