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The All-Ceramic Knee Endoprosthesis-The Gap Between Expectation and Experience with Ceramic Implants

机译:全陶瓷膝关节假体-陶瓷植入物的期望值与经验值之间的差距

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摘要

Total knee replacement (TKR) is a successful procedure in orthopedic surgery. In order to further improve survival rates and obtain optimal clinical outcome with higher range of motion, improvements in fixation and wear couples as well as specific designs have been made. The worldwide circulation of ceramics in total hip replacement is justified through its extreme wear and corrosion resistance because of the excellent tribological properties and the absence of electrochemical reactions. Using these advantages, as well as finding a solution in cases of hypersensitivity against metallic implant materials, led to the development of total knee replacement systems with ceramic components. However, ceramic materials are brittle and less resistant especially to impact load in comparison to metallic implants. This requires components with sufficient thickness on the tibial side, which can lead to increased bone loss. In particular, this may lead to inadequate stability and dislocation of the joint line. Furthermore, the tribological behavior of an all-ceramic total knee, i.e. the femoral and tibial component as well as the insert, is not clearly investigated so far. Therefore, all-ceramic knee endoprostheses are not feasible at the moment. There is still a need for further development and adequate preclinical testing of all-ceramic implants. Major prerequisite should be the optimization of existing designs of the femoral ceramic component.
机译:全膝关节置换术(TKR)在骨科手术中是成功的方法。为了进一步提高生存率并通过更大范围的运动获得最佳的临床结果,已经进行了固定和磨损对以及特殊设计的改进。全髋关节置换术中陶瓷的全球流通因其极高的耐磨性和耐腐蚀性而被证明是合理的,因为它具有出色的摩擦学性能和无电化学反应。利用这些优势,以及在对金属植入物材料过敏的情况下找到解决方案,导致了开发具有陶瓷组件的全膝关节置换系统。然而,与金属植入物相比,陶瓷材料是脆性的,尤其是抗冲击负载性更差。这需要在胫骨侧具有足够厚度的组件,这可能导致增加的骨丢失。特别是,这可能导致接头线的稳定性不足和错位。此外,迄今为止,还没有清楚地研究全陶瓷全膝关节的摩擦学行为,即股骨和胫骨组件以及插入物。因此,目前全陶瓷膝关节假体尚不可行。仍需要进一步开发和对全陶瓷植入物进行充分的临床前测试。主要前提应是优化股骨陶瓷组件的现有设计。

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