Scleredema adultorum (ScA; Buschke's disease) is a fibromucinous connective tissue disorder characterized by progressive induration of the skin of the neck, shoulder girdle, proximal parts of the upper extremities, and face (1, 2). Eosinophilic fasciitis (EF) is another entity characterized by progressive skin thickening, usually involving the extremities that can progress to 'peau d'orange' and then induration (3). We describe a woman with a diffuse scleroderma-like syndrome presenting with clinical and histopathological characteristics of both EF and ScA, 4 months after radiotherapy for endometrial cancer. Lesions in both diseases were extended beyond the radiation field and without recurrence of cancer.
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