Preparation of 3-Bromo-2-(Nitromethylene)pyrrolidine and 3-bromo-N-Methyl-1-Nitro-1-Buten-2-Amine

摘要

Since its discovery in the early 1970s,the nitromethylene class of insect control agents has received considerable attention within the agrochemical industry.Recently we had occasion to investigate a series of compounds(I)featuring the nitromethylene group in three slightly varied environments(Fig.I).Our approach required the syntheses of the allylic bromides 2a-c.Since the preparation of 2c is described in the literature,the same strategy was applied to the synthesis of 2b from nitromethylenepyrrolidine 3(Dq.1).