Homogeneous RuCl_2(PPh_3)_3-Catalyzed Regioselective Liquid-Phase Transfer Hydrogenation of Carbon-Carbon Double Bond in Chlorobenzylidene Ketones with Ethylene Glycol as Hydrogen Donor

摘要

The regioselective transfer hydrogenation of a carbon-carbon double bond of different chlorobenzylidene ketones is effectuated in ethylene glycol with a very high selectivity in the presence of homogeneous, tris(triphenylphosphine)ruthenium-(II) chloride catalyst. Different important process parameters such as temperature, catalyst loading, and reaction period are studied. The reaction follows a first-order kinetics, and the energy of activation was found to be 52 kJ/mol.