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Translabyrinthine approach for the management of large and giant vestibular schwannomas.

机译:经迷路方法治疗大型和巨大前庭神经鞘瘤。

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摘要

BACKGROUND: The removal of large vestibular schwannomas through the translabyrinthine approach is still controversial. MATERIALS AND METHODS: A retrospective review was performed of 81 patients (58 men and 23 women) with vestibular schwannomas 3 cm or greater, who underwent tumor removal via the translabyrinthine approach between 1985 and 2000. The mean tumor size was 3.7 +/- 0.81 cm, and the mean age of the patients was 47 +/- 16.1 years. The largest tumor was 6 cm. All surgical procedures were performed in collaboration with a neurosurgery team. RESULTS: Total tumor removal was accomplished in 77 cases (95.1%). The facial nerve was preserved anatomically in 69 (85.2%) of the patients. In 4 patients, divided nerves were repaired by primary anastomosis. Facial nerve function was assessed immediately after surgery and 1 year or more after discharge. Good function (House-Brackmann facial nerve Grade I or II) was present in 45% of patients and acceptable function (Grades I-IV) in 80% of patients 1 year after resection of the tumor. Cerebrospinal fluid leakage occurred in 12 patients (17%), meningitis developed in 3 patients (4%), and 1 patient experienced a stroke immediately after surgery. There were no deaths caused by surgery in this series. CONCLUSION: The translabyrinthine approach offers an excellent anatomical view of the cerebellopontine angle and a direct approach to the tumor with functional preservation of the facial nerve. Total removal is accomplished in most cases, with minimum incidence of morbidity and no incidence of mortality.
机译:背景:通过经迷路方法清除大前庭神经鞘瘤仍存在争议。材料与方法:回顾性分析了1985年至2000年间经经迷路方法切除的81例前庭神经鞘瘤3 cm或更大的患者(58例男性和23例女性)。平均肿瘤大小为3.7 +/- 0.81厘米,患者的平均年龄为47 +/- 16.1岁。最大的肿瘤是6厘米。所有外科手术均与神经外科团队合作进行。结果:77例(95.1%)的肿瘤全部切除。 69例(85.2%)的患者解剖保存了面神经。在4例患者中,原发性吻合修复了神经分裂。手术后和出院后一年或更长时间评估面神经功能。切除肿瘤1年后,有45%的患者表现出良好的功能(House-Brackmann面神经I或II级),有80%的患者表现出可接受的功能(I-IV级)。脑脊液漏发生12例(17%),脑膜炎发生3例(4%),并且1例患者在手术后立即中风。该系列没有因手术引起的死亡。结论:经迷路穿刺入路可提供小脑桥脑角的极佳解剖学视图,并可通过保留面神经功能直接进入肿瘤。在大多数情况下,可完全清除,发病率最低,无死亡。

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