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Adult Head and Neck Soft Tissue Sarcomas: Treatment and Outcome

机译:成人头颈部软组织肉瘤:治疗和结果

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We have retrospectively analysed the experience of a musculoskeletal oncological unit in the management of adult head and neck soft tissue sarcomas from 1990 to 2005. Thirty-six patients were seen, of whom 24 were treated at this unit, the remainder only receiving advice. The median age of the patients was 46 years. Most of the sarcomas were deep and of high or intermediate grade with a median size of 5.5 cm. Eleven different histological subtypes were identified. Wide excision was possible only in 21% of the cases. 42% of the patients developed local recurrence and 42% developed metastatic disease usually in the lungs. Overall survival was 49% at 5 years. Tumour size was the most important prognostic factor. Adult head and neck soft tissue sarcomas have a high mortality rate with a high risk of local recurrence and metastatic disease. The rarity of the disease would suggest that centralisation of care could lead to increased expertise and better outcomes.
机译:我们回顾性分析了1990年至2005年间肌肉骨骼肿瘤科治疗成人头颈部软组织肉瘤的经验。共检查了36例患者,其中24例在该部门接受了治疗,其余仅接受建议。患者的中位年龄为46岁。多数肉瘤较深,中等或中等等级,平均大小为5.5 cm。确定了11种不同的组织学亚型。仅在21%的病例中才可能进行广泛切除。 42%的患者通常在肺部发生局部复发,而42%的患者发生转移性疾病。 5年总生存率为49%。肿瘤大小是最重要的预后因素。成人的头部和颈部软组织肉瘤的死亡率高,局部复发和转移性疾病的风险也高。这种疾病的稀有性表明,集中医疗可以增加专业知识和改善结局。

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