The science-to-service gap in real-world schizophrenia treatment: the 95% problem.

摘要

One overwhelming, regrettable, and disheartening fact about the treatment of schizophrenia in the United States is that few people with this disorder receive well-recognized and highly effective treatments. This reality is known as the science-to-service gap: Intervention science has demonstrated with rigorous research methods that a number of interventions are effective, yet services research shows indisputably that people with this serious mental disorder are likely to receive few if any of these effective interventions. In this special theme issue, the authors review 3 aspects of this problem: first, the evidence for lack of effective services at the epidemiological and clinical levels; second, difficulties of clinical engagement and retention in services; and third, the widespread failure to implement and sustain effective interventions in routine practice settings.