Effects of Zataria multiflora boiss on experimental intestinal ischemia-reperfusion injury in male Wistar rats.

摘要

The effects of Zataria multiflora boiss (ZM) oral extract on intestinal ischemia/reperfusion (I/R) injury in Male Wistar rats is described. Rats were gavaged ZM 1 week before 45 m ischemia followed by 1h reperfusion (I/R) treatment. Groups of 5 rats each were gavaged with 1 ml ZM 200ppm +I/R and 1 ml ZM 400ppm +I/R. Controls were either gavaged 1 ml saline with I/R or gavaged 1 ml saline without I/R. At autopsy jejunum tissue was excised and examined microscopically. I/R controls showed severe mucosal damage whereas those given ZM appeared to have less or no damage.