A Highly Efficient Synthesis of the FGH Ring of Micrandilactone A.Application of Thioureas as Ligands in the Co-catalyzed Pauson-Khand Reaction and Pd-Catalyzed Carbonylative Annulation

摘要

The functionalized FGH ring system of micrandilactone A was successfully constructed in high selectivity and good yields.The key reactions in our strategy are the Co-thiourea-catalyzed stereoselective,intramolecular Pauson-Khand reaction and Pd-thiourea-catalyzed stereoselective,intramolecular annulation.