'A Sledgehammer Breaks Glass but Forges Steel': Bacteria Adhesion Shapes Gut Immunity

摘要

Gut bacteria are known to affect immune cell development, but most intestinal lymphocytes have no direct contact with luminal bacteria. Two studies by Atarashi et al. and Sano et al. shed light on how bacterial adhesion can cue intestinal epithelial cells to direct differentiation of gut T cells.