The nuclei of progenitor cells in developing neural epithelia change their position during the cell cycle through a process called interkinetic nuclear migration. Del Bene et al. (2008) report that defects in the machinery controlling this process lead to altered exposure to Notch signals and systemic effects on neurogenesis in the retina.
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机译:发育中的神经上皮细胞中的祖细胞核在细胞周期中通过称为运动间核迁移的过程改变其位置。 Del Bene等。 (2008年)报告说,控制该过程的机械缺陷导致Notch信号暴露的改变和对视网膜神经发生的系统性影响。
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