A selective sorbent for removing bacterial endotoxins from blood

摘要

Synthetic ligands carrying a positive charge and capable of selective binding of bacterial endotoxins are covalently immobilized on surfaces of domestic hemosorbent Styrosorb-514 based on hypercrosslinked polystyrene. It is shown that the resulting sorbent aimed at treating sepsis exceeds imported specific hemosorbent in Toraymyxin (TM) columns in removing lipopolysaccharides, and can be used in domestically-produced Desepta columns.