Synthesis of 4-Aryl-6-phenyl-2-thioxo-1,2-dihydropyridine-3-carbonitriles by Three-Component Condensationof Aromatic Aldehydes with Cyanothioacetamideand 4,4,4-Trifluoro-1-phenylbutane-1,3-dione

摘要

4-Aryl-6-pheny]-2-thioxo-1,2-dihydropyridine-3-carbonitriles were synthesized by three-component condensation of aromatic aldehydes with cyanothioacetamide and 4.4,4-trifluoro-1-phenylbutane-1,3-dione. The reaction involved initial formation of Michael adducts which underwent acyl cleavage.