Microwave assisted synthesis and characterization of novel hydrazone derivatives

摘要

A simple and efficient method has been developed for the synthesis of O-alkyl alkyl-1-(4-substituted benzylidene) phosphonohydrazone derivatives (3a-j) using silica supported microwave irradiation technique under solvent free conditions. The series of phosphonohydrazone derivatives were synthesized by the condensation reaction of O-alkyl alkylphospho-rohydrazides (1a-e) with substituted benzaldehydes. The synthesized compounds were structurally confirmed by elemental analysis, FT-IR, ~1H NMR and mass spectroscopy.