Reactions of Esters of Cyclopropylfurancarboxylic Acids in the System Paraform-Hydrogen Chloride-Zinc Chloride and Phosphorylation of Reaction Products

摘要

Ethyl 2- and 5-cyclopropylfuran-3-carboxylates react with the system comprising Paraform,hydrogen chloride,and zinc chloride to form chloromethyl derivatives.This process is accompanied by selective cleavage of the cyclopropane ring,leading to appearance of a gamma-chloropropyl fragment.Phosphorylation of the resulting halides with sodium diethyl phosphite in benzene involves exclusively the chloromethyl group.