Phosphorylation of Per-6-O-[(tert-butyl)dimethylsilyl]-peta-cyclodextrin with Tetraethylphosphorodiamidochloridite

摘要

Phosphorylation of beta-cyclodextrin with protected primary hydroxy groups with tetraethylphos-phorodiamidochloridite,contrary to phosphorylation with hexaethylphosphorous triamide,proceeds irregularly and leads to compounds with mixed functions,whose ratio depends on reaction conditions.