Absolute Configurational Assignment in Chiral Compounds through Vibrational Circular Dichroism (VCD) Spectroscopy

摘要

Trends and perspectives of the IR/VCD chiroptical technique in configurational and conformational assignment of chiral compounds are illustrated with significant examples from literature reports within 2003-2008 period. The advantages, as well as inherent limitations of VCD as complementary or competing technique to the classical chiroptical methods are underlined.