Study of Serum and Saliva Biochemical Levels for Copper, Zinc and Cooper-Zinc Imbalance in Patients with Oral Cancer and Oral Potentially Malignant Disorders and their Prostetical and DSSS (Disfunctional Syndrome of Stomatognathic System) Treatment

摘要

The significant increase of the prevalence of oral cancer and oral potentially malignant disorders determined a lot of countries to integrate this pathology amongst the main public health problems of dental medicine. Apart from the essential role of copper and zinc in the functions of human body, it seems that changes in the serum and saliva levels of zinc and copper may play a role in the pathogenesis of oral cancer. The aim of this study was to measure the serum levels of copper and zinc in patients with oral cancer and oral potentially malignant disorders. In conclusions, the serum and saliva levels of copper in oral cancer were significantly higher than in healthy controls subjects.