Development of the Sjogren's Syndrome Responder Index, a data-driven composite endpoint for assessing treatment efficacy

Cornec Divi; Devauchelle-Pensec Valerie; Mariette Xavier; Jousse-Joulin Sandrine; Berthelot Jean-Marie; Perdriger Aleth; Puechal Xavier; Le Guern Veronique; Sibilia Jean; Gottenberg Jacques-Eric; Chiche Laurent; Hachulla Eric; Hatron Pierre Yves; Goeb Vincent; Hayem Gilles; Morel Jacques; Zarnitsky Charles; Dubost Jean Jacques; Seror Raphaele; Pers Jacques-Olivier; Meiners Petra M.; Vissink Arjan; Bootsma Hendrika; Nowak Emmanuel; Saraux Alain

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Development of the Sjogren's Syndrome Responder Index, a data-driven composite endpoint for assessing treatment efficacy

机译：舍格伦综合症候群指数的发展，这是一种数据驱动的综合终点，用于评估治疗效果

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Objectives. To determine which outcome measures detected rituximab efficacy in the Tolerance and Efficacy of Rituximab in Sjogren's Disease (TEARS) trial and to create a composite endpoint for future trials in primary SS (pSS).

机译：目标。要确定哪些结局指标在干燥综合征（TEARS）试验中在利妥昔单抗的耐受性和功效中检测到利妥昔单抗的疗效，并为将来在原发性SS（pSS）中的试验创建复合终点。

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《Rheumatology》 |2015年第9期|共10页
作者
Cornec Divi; Devauchelle-Pensec Valerie; Mariette Xavier; Jousse-Joulin Sandrine; Berthelot Jean-Marie; Perdriger Aleth; Puechal Xavier; Le Guern Veronique; Sibilia Jean; Gottenberg Jacques-Eric; Chiche Laurent; Hachulla Eric; Hatron Pierre Yves; Goeb Vincent; Hayem Gilles; Morel Jacques; Zarnitsky Charles; Dubost Jean Jacques; Seror Raphaele; Pers Jacques-Olivier; Meiners Petra M.; Vissink Arjan; Bootsma Hendrika; Nowak Emmanuel; Saraux Alain;
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正文语种 eng
中图分类免疫性疾病;
关键词
primary Sjogren's syndrome; rituximab; efficacy; outcome measures;

机译：原发性干燥综合征;利妥昔单抗;疗效;结果指标;

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1. Development of the Sjogren's Syndrome Responder Index, a data-driven composite endpoint for assessing treatment efficacy [J] . Cornec Divi, Devauchelle-Pensec Valerie, Mariette Xavier, Rheumatology . 2015,第9期

机译：舍格伦综合症候群指数的发展，这是一种数据驱动的综合终点，用于评估治疗效果
2. Hypergammaglobulinemic purpura of waldenstorm associated with sjogren’s syndrome in a young female responding to rituximab treatment [J] . Neeraj Jain, Lalit Duggal Case Reports in Clinical Medicine . 2013,第2期

机译：一名对利妥昔单抗治疗有反应的年轻女性，患有瓦尔定风暴的高γ-珠蛋白性紫癜与干燥综合征相关
3. Hypergammaglobulinemic purpura in two sisters with Sjogren's syndrome responding to colchicine treatment. [J] . Habib GS, Nashashibi M Clinical rheumatology . 2004,第2期

机译：秋水仙综合征的两个姐妹对秋水仙碱的治疗反应有高γ-γ-珠蛋白性紫癜。
4. Characterizing Restorative Dental Treatments of Sjogren's Syndrome Patients Using Electronic Dental Records Data [C] . Zasim Siddiqui, Yue Wang, Payal Makkad, MEDINFO . 2017

机译：使用电子牙科记录数据表征Sjogren综合征患者的恢复性牙科治疗
5. Proteomic Study of Oral Cancer Stem-Like Cells and Bone Marrow Cell Treatment for Sjogren's Syndrome. [D] . Misuno, Kaori. 2013

机译：干燥癌症干细胞样蛋白质组学研究和骨髓细胞治疗干燥综合征。
6. EULAR Sjogrens syndrome disease activity index: development of a consensus systemic disease activity index for primary Sjogrens syndrome [O] . Raphaèle Seror, Philippe Ravaud, Simon Bowman, -1

机译：欧洲Sjogren的综合征疾病活动指数：发育原发性Sjogren综合征的共识全身疾病活动指数
7. American College of Rheumatology classification criteria for Sjogren's syndrome: A data-driven, expert consensus approach in the Sjogren's International Collaborative Clinical Alliance Cohort [O] . Shiboski S. C., Shiboski C. H., Criswell L. A., 2012

机译：美国风湿病学院干燥综合征综合分类标准：以数据驱动的专家共识方法在干燥医学国际合作临床联盟研究中

Development of the Sjogren's Syndrome Responder Index, a data-driven composite endpoint for assessing treatment efficacy

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