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Role of spirometric and arterial gas data in predicting pulmonary complications after abdominal surgery.

机译:肺活量和动脉气体数据在预测腹部手术后肺部并发症中的作用。

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摘要

The aim of this study was to evaluate the predictive value of preoperative spirometric and arterial gas data on severe pulmonary complications (PC) after elective abdominal surgery. We retrospectively studied 480 patients, 254 males and 226 females, mean (SD) age 63 (11) years, at risk for PC according to standardized criteria, who underwent laparotomy for resection of gallbladder for gallstones (44% of patients), resection of colon, rectum or stomach for malignant tumours (37%), and other abdominal surgery (19%). The overall incidence of postoperative PC was 18%. In a logistic regression analysis adjusted for smoking habit and clinical history of chronic bronchitis, FEV1<61% of predicted [odds ratio (OR)=16.86, 95% confidence interval (95%CI)=5.62-50.58] and PaO2<9.33 kPa (OR=6.42, 95%CI=2.48-16.61) were the main determinants of PC. Ischaemic heart disease (OR=3.44, 95%CI=1.08-10.93), operation for malignant tumours (OR=3.24, 95%CI=1.75-6.00) and age (OR=1.04, 95%CI=1.00-1.08) were also independent predictors of PC. Patients with moderate-to-severe airway obstruction combined with hypoxaemia had a significant higher risk of PC in comparison with patients with a normal respiratory pattern. Taking into account age, type of operation, and comorbidity, a preoperative respiratory functional assessment could be useful in identifying an increased risk of major PC in selected patients.
机译:这项研究的目的是评估择期腹部手术后术前肺活量和动脉气体数据对严重肺部并发症(PC)的预测价值。我们根据标准化标准回顾性研究了480例患者,其中254例男性和226例女性,平均(SD)年龄为63(11)岁,有发生PC的危险,他们接受了剖腹手术切除胆囊结石(44%的患者)。结肠,直肠或胃恶性肿瘤(37%),以及其他腹部手术(19%)。术后PC的总发生率为18%。在根据吸烟习惯和慢性支气管炎的临床病史进行的逻辑回归分析中,FEV1 <预测的[比值比(OR)= 16.86、95%的置信区间(95%CI)= 5.62-50.58]的61%和PaO2 <9.33 kPa (OR = 6.42,95%CI = 2.48-16.61)是PC的主要决定因素。缺血性心脏病(OR = 3.44,95%CI = 1.08-10.93),恶性肿瘤手术(OR = 3.24,95%CI = 1.75-6.00)和年龄(OR = 1.04,95%CI = 1.00-1.08)为也是PC的独立预测因子。与正常呼吸模式的患者相比,中度至重度气道阻塞并伴有低氧血症的患者发生PC的风险显着更高。考虑到年龄,手术类型和合并症,术前进行的呼吸功能评估可能有助于确定某些患者发生主要PC的风险增加。

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