Diels-Alder dimerization of Morita-Baylis-Hillman acetates catalyzed by organocatalysts

摘要

DABCO-catalyzed dimerization of Morita-Baylis-Hillman acetates to synthesize a series of 3-alkyl-4-(E)-alkenyl-cyclohex-1-ene-1,4-dicarbonyl compounds in excellent yields with modest to excellent diastereoselectivity is reported. A plausible reaction mechanism is also proposed on the basis of previous literature and preliminary investigation the asymmetric version of the reaction.