Practical, efficient synthesis of N-mono-substituted β-amino tertiary thiols via reductive ring-opening of 3-thiazolines

摘要

An efficient synthesis of N-mono-substituted β-amino tertiary thiols by reductive ring-opening of 3-thiazolines, obtained by use of the Asinger reaction, is described. This synthesis be regarded as a complementary approach for aminolytic ring-opening of thiiranes.