Pretransplant urinary proteome analysis does not predict development of chronic kidney disease after liver transplantation

摘要

Background & AimsChronic kidney disease (CKD) is a common complication after liver transplantation. Kidney biopsies cannot be easily performed before liver transplantation to predict patients at high risk for CKD. The aim of our study was to determine whether pre-, peri- and post-transplant factors, as well as peptides present in preliver transplant urine samples were associated with loss in kidney function at 6months post-transplantation using proteome analysis.