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Pediatric chest and abdominopelvic CT: Organ dose estimation based on 42 patient models

机译:小儿胸部和腹盆腔CT:基于42个患者模型的器官剂量估算

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Purpose: To estimate organ dose from pediatric chest and abdominopelvic computed tomography (CT) examinations and evaluate the dependency of organ dose coefficients on patient size and CT scanner models. Materials and Methods: The institutional review board approved this HIPAA-compliant study and did not require informed patient consent. A validated Monte Carlo program was used to perform simulations in 42 pediatric patient models (age range, 0-16 years; weight range, 2-80 kg; 24 boys, 18 girls). Multidetector CT scanners were modeled on those from two commercial manufacturers (LightSpeed VCT, GE Healthcare, Waukesha, Wis; SOMATOM Definition Flash, Siemens Healthcare, Forchheim, Germany). Organ doses were estimated for each patient model for routine chest and abdominopelvic examinations and were normalized by volume CT dose index (CTDIvol). The relationships between CTDI vol-normalized organ dose coefficients and average patient diameters were evaluated across scanner models. Results: For organs within the image coverage, CTDIvol-normalized organ dose coefficients largely showed a strong exponential relationship with the average patient diameter (R 2 0.9). The average percentage differences between the two scanner models were generally within 10%. For distributed organs and organs on the periphery of or outside the image coverage, the differences were generally larger (average, 3%-32%) mainly because of the effect of overranging. Conclusion: It is feasible to estimate patient-specific organ dose for a given examination with the knowledge of patient size and the CTDIvol. These CTDIvol-normalized organ dose coefficients enable one to readily estimate patient-specific organ dose for pediatric patients in clinical settings. This dose information, and, as appropriate, attendant risk estimations, can provide more substantive information for the individual patient for both clinical and research applications and can yield more expansive information on dose profiles across patient populations within a practice.
机译:目的:通过小儿胸部和腹部盆腔计算机断层扫描(CT)检查评估器官剂量,并评估器官剂量系数对患者体型和CT扫描仪模型的依赖性。材料和方法:机构审查委员会批准了该符合HIPAA的研究,无需患者知情同意。经过验证的蒙特卡洛程序用于对42种儿科患者模型(年龄范围为0-16岁;体重范围为2-80千克; 24个男孩为18个女孩)进行模拟。 Multidetector CT扫描仪以两个商业制造商(LightSpeed VCT,GE Healthcare,Waukesha,Wis; SOMATOM Definition Flash,Siemens Healthcare,Forchheim,德国)的产品为模型。估计每种患者模型的器官剂量以进行常规的胸部和腹部盆腔检查,并通过体积CT剂量指数(CTDIvol)进行标准化。在扫描仪模型之间评估了CTDI体积归一化器官剂量系数与平均患者直径之间的关系。结果:对于图像覆盖范围内的器官,CTDIvol归一化的器官剂量系数在很大程度上与平均患者直径呈强指数关系(R 2> 0.9)。两种扫描仪型号之间的平均百分比差异通常在10%以内。对于分布的器官以及图像覆盖范围外围或外部的器官,差异通常较大(平均为3%-32%),这主要是由于范围过大的影响。结论:在了解患者人数和CTDIvol的情况下,估算给定检查的患者特定器官剂量是可行的。这些CTDIvol归一化的器官剂量系数使人们可以轻松地估计临床环境中小儿患者的患者特定器官剂量。该剂量信息以及适当的伴随风险估计,可以为单个患者提供更多的临床和研究应用的实质性信息,并且可以在实践中针对患者群体的剂量分布提供更广泛的信息。

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