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Empirically derived latent classes of tobacco dependence syndromes observed in recent-onset tobacco smokers: Epidemiological evidence from a national probability sample survey

机译:在最近发作的吸烟者中观察到的根据经验得出的烟草依赖综合症的潜在类别:来自国家概率抽样调查的流行病学证据

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This study pursued a line of large-sample epidemiological research on tobacco dependence syndromes that may appeal during the first 2 years of tobacco smoking, as clinical features begin to emerge. Focusing on smokers who just recently started using tobacco may provide insights into the transitions that lead from initial smoking toward tobacco dependence. A specific focus was a possible excess risk of tobacco dependence associated with early-onset smoking. Data came from public use files of the 1995-1998 National Household Surveys on Drug Abuse. Analyses were based on responses from 2,993 smokers, that is, those whose age at onset of tobacco smoking was either equal to the age at the time of the interview (n = 1,030) or within 1 year of the age at the interview (n =1,963). Seven clinical features were assessed for a measure of the tobacco dependence syndrome, elicited during a standardized assessment. Findings from latent class analysis best support a model with three classes of smokers; features of tobacco dependence are prominent in just two of these classes, which in aggregate constitute 29% of the recent-onset smokers. Earlier-onset tobacco smokers may have a modestly higher probability of expressing dependence features within 2 years of smoking onset, compared with later-onset smokers (i.e., those starting after age 20). Clinical features of tobacco dependence emerge within 1-2 years after the onset of smoking. If the three-class model of tobacco dependence is correct, early-onset smoking may confer modest excess risk of becoming tobacco dependent during the first 2 years after smoking onset.
机译:这项研究针对烟草依赖综合症进行了一系列大样本流行病学研究,随着临床特征的开始出现,这些现象可能在吸烟的前两年中很有吸引力。关注刚刚开始使用烟草的吸烟者,可能会提供从最初吸烟到烟草依赖的过渡的见解。一个特别的重点是与早发吸烟相关的烟草依赖的可能过度风险。数据来自1995-1998年全国家庭滥用药物调查的公共使用档案。分析基于来自2,993名吸烟者的答复,即那些吸烟开始时的年龄等于访谈时的年龄(n = 1,030)或访谈时年龄的1年内(n = 1,963)。评估了七个临床特征,以评估标准化评估过程中引起的烟草依赖综合症。潜在类别分析的结果最好地支持具有三类吸烟者的模型。烟草依赖的特征仅在这两个类别中就很突出,合起来占最近发作的吸烟者的29%。与较晚发作的吸烟者(即20岁以后开始吸烟的人)相比,较早发作的吸烟者在发病2年内可能有较高的表达依赖特征的可能性。吸烟开始后1-2年内就会出现烟草依赖的临床特征。如果三类烟草依赖模型是正确的,那么在吸烟开始后的头两年内,早发吸烟可能会给适度的过度依赖烟瘾的风险。

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