Simple and Fast SPE-UPLC~(TM)-MS-MS Method for an Allergy Talbet Mixture of Acids and Bases

摘要

We have previously introduced a novel approach to selecting W W SPE methodology based on two protocols and four mixed-mode Oasis? sorbents. Proof of concept studies yielded positive results when knowledge of the samples' chemical properties were used to choose the correct sorbent and protocol. We have successfully taken this approach one step further and applied it to plasma samples containing die components of a commercial allergy and sinus combination tablet.